(R,S)-MDMA
(R,S)-MDMA acts as a partial agonist of 5-HT2A, 5-HT2B and 5-HT2C receptors. (R,S)-MDMA belongs to psychoactive substances. (R,S)-MDMA exhibits antidepressant activity. (R,S)-MDMA can be used for research on mental disorders such as post-traumatic stress disorder and depression.
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- CAS No.: 859811-50-0
- Formule: C12H16O2
- Masse moléculaire:192.25
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Activité biologique
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Chemical Information
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Activité biologique
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5-HT2B Receptor 52.2 nM (Kd) |
5-HT2C Receptor 158 nM (EC50) |
5-HT2A Receptor 249 nM (EC50) |
(R,S)-MDMA (55 min) acts as a partial agonist of 5-HT2A, 5-HT2B, and 5-HT2C receptors in HEK293T cells, with EC50 values of 249 nM, 52.2 nM, and 158 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Administration of (R,S)-MDMA (7.5 mg/kg; i.p.) during training induces significant social conditioned place preference in C57BL/6J mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6J mice (9-13 weeks old)[1]
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Dosage:7.5 mg/kg
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Administration:i.p.; single dose
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Result:Increased social interaction compared to vehicle controls over the 25-min exploration period.
Showed the largest difference in prosocial behavior compared to vehicle during the final 10 min of the 30-min assay.
Chemical Information
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CAS No. 859811-50-0
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Masse moléculaire 192.25
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Formule C12H16O2
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SMILES
CC(CC1=CC2=C(C=C1)OCO2)CC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R,S)-MDMA Related Classifications
HY-186170B Related Classifications
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