SAL-0010042
SAL-0010042 is the inhibitor for Plasmodium phosphodiesterase β (PDEβ), that inhibits the hydrolysis of cAMP and cGMP (IC50=48.9 nM) in gametocytes, activates PKG, and inhibits the growth and development of Plasmodium (IC50 for 3D7 and Dd2 is 142 nM and 218 nM). SAL-0010042 inhibits hPDE5 and hPDE6 with IC50 of 632 nM and 73 nM.
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- CAS No.: 521298-46-4
- Formule: C15H15FN4O
- Masse moléculaire:286.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Activité biologique
Chemical Information
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CAS No. 521298-46-4
-
Masse moléculaire 286.30
-
Formule C15H15FN4O
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SMILES
O=C1N=C(CC2=C(F)C=CC=C2)NC3=C1NN=C3C(C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SAL-0010042 Related Classifications
HY-170431 Related Classifications
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