UA2239
UA2239 is an antimalarial agent and acyclic nucleoside phosphonate. UA2239 disrupts the essential cGMP-dependent egress pathway by decreasing cGMP levels. UA2239 targets guanylyl cyclase α. UA2239 demonstrates rapid and irreversible inhibitory effects on Plasmodium parasites.
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- CAS No.: 2455422-89-4
- Formule: C9H12N5Na2O5P
- Masse moléculaire:347.18
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
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Plasmodium |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
1000 μM
Compound: (R)-5
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Toxicity in human K562 cells assessed as effect on cell growth measured after 24 hrs by [3H]thymidine incorporation based assay
Toxicity in human K562 cells assessed as effect on cell growth measured after 24 hrs by [3H]thymidine incorporation based assay
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[PMID: 32687714] |
Chemical Information
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CAS No. 2455422-89-4
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Masse moléculaire 347.18
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Formule C9H12N5Na2O5P
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SMILES
O=C1NC(N)=NC2=C1N=CN2CC[C@H](CP(O[Na])(O[Na])=O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UA2239 Related Classifications
HY-179656 Related Classifications
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