112303-17-0
Chemical Structure
Cafamycin
- CAS No.: 112303-17-0
- Formula:C30H41NO4
- Molecular Weight:479.65
IUPAC Name: (R)-2-((2R,5S,6R)-6-((3E,5E)-6-((3aR,4S,5R,7aS)-4-(1H-pyrrole-2-carbonyl)-2,3,3a,4,5,7a-hexahydro-1H-inden-5-yl)hexa-3,5-dien-3-yl)-5-methyltetrahydro-2H-pyran-2-yl)butanoic acid
InChIKey: XINFXFISYDXMAU-AUQLTCFDSA-N
SMILES: O=C(C1=CC=CN1)[C@H]2[C@@]3([H])[C@](CCC3)([H])C=C[C@H]2/C=C/C=C([C@@H]4O[C@@](CC[C@@H]4C)([H])[C@@H](CC)C(O)=O)\CC
Biological Activity: Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin[1][2].
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Cafamycin | Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin. | |||||||||||||||||||||
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- [1]. Murenets NV, et al. Kafamitsin--novyĭ pirroléfirnyĭ antibiotik [Kafamycin--a new pyrrol ether antibiotic]. Antibiot Med Biotekhnol. 1987 Nov;32(11):811-4. [Content Brief]
- [2]. Li C, et al. Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167. Chembiochem. 2009 Apr 17;10(6):1064-72. [Content Brief]
Keywords
