2252278-57-0
Chemical Structure
Apoptosis inducer 7
- CAS No.: 2252278-57-0
- Formula:C49H68N2O7
- Molecular Weight:797.07
IUPAC Name: tert-butyl 4-(2-((4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS,E)-11-((benzyloxy)carbonyl)-4,4,6a,6b,8a,11,14b-heptamethyl-3,14-dioxo-3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-octadecahydropicen-2(1H)-ylidene)acetamido)piperidine-1-carboxylate
InChIKey: KYDXNZGGBRYTHC-GJLAEWTHSA-N
SMILES: C[C@]12[C@@](C(C=C3[C@]2(CC[C@@]4([C@@]3([H])C[C@](C)(CC4)C(OCC5=CC=CC=C5)=O)C)C)=O)([H])[C@@]6([C@@](C(C)(C(/C(C6)=C/C(NC7CCN(CC7)C(OC(C)(C)C)=O)=O)=O)C)([H])CC1)C
Biological Activity: Apoptosis inducer 7 (Compound 5I) induces apoptosis in cancer cells. Apoptosis inducer 7 inducrs cleavage of PARP, caspases, down-regulation of anti-apoptotic protein c-Flip and up regulation of pro-apoptotic protein Noxa. Apoptosis inducer 7 exhibits antitumor activity[1].
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Apoptosis inducer 7 | Apoptosis inducer 7 (Compound 5I) induces apoptosis in cancer cells. Apoptosis inducer 7 inducrs cleavage of PARP, caspases, down-regulation of anti-apoptotic protein c-Flip and up regulation of pro-apoptotic protein Noxa. Apoptosis inducer 7 exhibits antitumor activity. | |||||||||||||||||||||
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Keywords
