2357111-30-7
2357111-30-7
Chemical Structure
CRBN ligand-858
- CAS No.: 2357111-30-7
- Formula:C21H28ClN5O5
- Molecular Weight:465.94
IUPAC Name: 5-(4-(2-(2-aminoethoxy)ethyl)piperazin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
InChIKey: GQLARJAHIBHOLM-UHFFFAOYSA-N
SMILES: Cl.O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCN(CCOCCN)CC4
Biological Activity: CRBN ligand-858 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-858 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-858 | CRBN ligand-858 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-858 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
