2626934-64-1
Chemical Structure
c-ABL-IN-3
- CAS No.: 2626934-64-1
- Formula:C17H11F3N4O3
- Molecular Weight:376.29
IUPAC Name: 6-oxo-1-(pyrimidin-5-yl)-N-(4-(trifluoromethoxy)phenyl)-1,6-dihydropyridine-3-carboxamide
InChIKey: HWRMOIALGKRORG-UHFFFAOYSA-N
SMILES: O=C(C(C=C1)=CN(C2=CN=CN=C2)C1=O)NC3=CC=C(OC(F)(F)F)C=C3
Biological Activity: c-ABL-IN-3 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-3 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 50)[1].
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c-ABL-IN-3 | c-ABL-IN-3 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-3 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 50). | |||||||||||||||||||||
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Keywords
