60-80-0
60-80-0
Chemical Structure
Antipyrine
Synonym(s): Phenazone; Phenazon
- CAS No.: 60-80-0
- Formula:C11H12N2O
- Molecular Weight:188.23
IUPAC Name: 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
InChIKey: VEQOALNAAJBPNY-UHFFFAOYSA-N
SMILES: O=C1N(C2=CC=CC=C2)N(C)C(C)=C1
Biological Activity: Antipyrine (Phenazone) is an orally active antipyretic and analgesic. Antipyrine can be used as a probe agent for oxidative agent metabolism. Antipyrine also delays gastric emptying (GE) in rats[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Antipyrine | 99.93% | Antipyrine (Phenazone) is an orally active antipyretic and analgesic. Antipyrine can be used as a probe agent for oxidative agent metabolism. Antipyrine also delays gastric emptying (GE) in rats. | ||||||||||||||||||||
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Antipyrine (Standard) | ≥98% | Antipyrine (Standard) is the analytical standard of Antipyrine. This product is intended for research and analytical applications. Antipyrine (Phenazone) is an antipyretic and analgesic. Antipyrine can be used as a probe agent for oxidative agent metabolism. Antipyrine has been widely used in assessment of hepatic oxidative capacity. | ||||||||||||||||||||
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Antipyrine-d3 | 99.91% | Antipyrine-d3 is the deuterium labeled Antipyrine. Antipyrine (Phenazone) is an antipyretic and analgesic. Antipyrine can be used as a probe agent for oxidative agent metabolism. Antipyrine has been widely used in assessment of hepatic oxidative capacity. | ||||||||||||||||||||
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References
- [1]. Stevenson, I.H., Factors influencing antipyrine elimination. Br J Clin Pharmacol, 1977. 4(3): p. 261-5. [Content Brief]
- [2]. Engel G, et, al. Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Clin Pharmacol Ther. 1996 Jun;59(6):613-23. [Content Brief]
- [3]. RENKIN EM. Capillary and cellular permeability to some compounds related to antipyrine. Am J Physiol. 1953 Apr;173(1):125-30. [Content Brief]
- [4]. Soares AC, et al. Effect of antipyrine on the gastric emptying of liquid in rats. Braz J Med Biol Res. 2006 Nov;39(11):1507-12. [Content Brief]
