6272-55-5
![7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-w011640.gif "7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol Chemical Structure")
6272-55-5
Chemical Structure
7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol
- CAS No.: 6272-55-5
- Formula:C20H16O
- Molecular Weight:272.35
IUPAC Name: 7,8,9,10-tetrahydrobenzo[pqr]tetraphen-7-ol
InChIKey: VKUQFYXBPGXTKI-UHFFFAOYSA-N
SMILES: OC1CCCC2=C3C=CC4=CC=CC5=C4C3=C(C=C21)C=C5
Biological Activity: 7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters[1], which are capable of forming covalent DNA adducts and inducing mutations[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol | 98.09% | 7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters, which are capable of forming covalent DNA adducts and inducing mutations. | ||||||||||||||||||||
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References
- [1]. Glatt H, Pauly K, Frank H, Seidel A, Oesch F, Harvey RG, Werle-Schneider G. Substance-dependent sex differences in the activation of benzylic alcohols to mutagens by hepatic sulfotransferases of the rat. Carcinogenesis. 1994 Nov;15(11):2605-11. [Content Brief]
- [2]. Surh YJ, Tannenbaum SR. Sulfotransferase-mediated activation of 7,8,9,10-tetrahydro-7-ol, 7,8-dihydrodiol, and 7,8,9,10-tetraol derivatives of benzo[a]pyrene. Chem Res Toxicol. 1995 Jul-Aug;8(5):693-8. [Content Brief]
