951151-97-6
Chemical Structure
JNJ-38158471
- CAS No.: 951151-97-6
- Formula:C15H17ClN6O3
- Molecular Weight:364.79
IUPAC Name: (E)-1-(4-((6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)oxy)-2-chlorophenyl)-3-ethylurea
InChIKey: BJHCYTJNPVGSBZ-QPSGOUHRSA-N
SMILES: O=C(NCC)NC1=CC=C(OC2=NC=NC(N)=C2/C=N/OC)C=C1Cl
Biological Activity: JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
JNJ-38158471 | 97.02% | JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords