Clcnka - chloride channel, voltage-sensitive Ka Gene

Also Known as CLC-K1; Clcnk1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12733

Summary

This gene is a member of the CLC family of voltage-gated chloride channels. The gene is located adjacent to a highly similar Chloride Channel gene on chromosome 4. This gene is syntenic with human CLCNKB (geneID:1188). Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Sep 2009]

Clcnka Products (2)

mRNA Protein Name
NM_001146307.1 NP_001139779.1 chloride channel protein ClC-Ka
NM_024412.3 NP_077723.3 chloride channel protein ClC-Ka

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables chloride channel activity IDA
IDA: Inferred from direct assay
23791703 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11734858 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within regulation of body fluid levels IMP
IMP: Inferred from mutant phenotype
11133517 MGI
acts upstream of or within renal inner medulla development IMP
IMP: Inferred from mutant phenotype
11423561 MGI
involved in transepithelial chloride transport IMP
IMP: Inferred from mutant phenotype
9916798 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
11423561 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chloride channel protein ClC-Ka

  • chloride channel K1

  • chloride channel Ka

  • putative basolateral cTAL chloride channel ClC-Ka

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS02760 CLCNKA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clcnka NCBI NCBI:1187