Mmp20 - matrix metallopeptidase 20 (enamelysin) Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 30800

Summary

This gene encodes a member of the matrix metalloproteinase family of zinc-dependent endopeptidases capable of degrading extracellular matrix proteins. This gene is expressed specifically in the ameloblasts and odontoblasts, and the encoded protein is an inactive zymogen that requires proteolytic removal of a N-terminal propeptide to become enzymatically active. Mice lacking the encoded protein display an amelogenesis imperfecta phenotype. [provided by RefSeq, Oct 2015]

Mmp20 Products (1)

mRNA Protein Name
NM_013903.2 NP_038931.1 matrix metalloproteinase-20 preproprotein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within amelogenesis IMP
IMP: Inferred from mutant phenotype
15557396 MGI
acts upstream of or within extracellular matrix disassembly IMP
IMP: Inferred from mutant phenotype
22243248 MGI
acts upstream of or within protein catabolic process IMP
IMP: Inferred from mutant phenotype
22243248 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

matrix metalloproteinase-20

  • enamel metalloproteinase

  • matrix metalloproteinase 20 (enamelysin)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08540 MMP20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08544 MMP25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19220 Mmp25 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mmp20 NCBI NCBI:9313