Vti1a - vesicle transport through interaction with t-SNAREs 1A Gene

Also Known as Vti1; DD6A4-2(1)

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65277

Summary

Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport; synaptic vesicle to endosome fusion; and vesicle fusion with Golgi apparatus. Located in several cellular components, including cytoplasmic vesicle; neuronal cell body; and perinuclear region of cytoplasm. Part of SNARE complex. Orthologous to human VTI1A (vesicle transport through interaction with t-SNAREs 1A). [provided by Alliance of Genome Resources, Apr 2022]

Vti1a Products (1)

mRNA Protein Name
NM_023101.1 NP_075589.1 vesicle transport through interaction with t-SNAREs homolog 1A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
24882364 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in endoplasmic reticulum to Golgi vesicle-mediated transport IDA
IDA: Inferred from direct assay
16735505 RGD
involved in synaptic vesicle to endosome fusion IDA
IDA: Inferred from direct assay
17004320 RGD
involved in synaptic vesicle to endosome fusion IMP
IMP: Inferred from mutant phenotype
17004320 RGD
involved in vesicle fusion with Golgi apparatus IDA
IDA: Inferred from direct assay
16735505 RGD
Cellular Component GO Annotation Evidence Verweise Source
part of SNARE complex IDA
IDA: Inferred from direct assay
10908612 RGD
located in clathrin-coated vesicle IDA
IDA: Inferred from direct assay
10908612 RGD
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
10908612 RGD
located in neuron projection terminus IDA
IDA: Inferred from direct assay
10908612 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10908612 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
10908612 RGD
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
10908612 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
10908612 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
12067063 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicle transport through interaction with t-SNAREs homolog 1A

  • SNARE Vti1a-beta protein

  • vesicle transport v-SNARE protein Vti1-like 2

  • vti1-rp2

Vti1a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Cross
Vti1a Q9JI51 Syt11 Mus musculus Q9R0N3
Pull Down
24882364
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15722 VTI1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20519 Vti1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27028 Vti1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vti1a NCBI NCBI:143187