POLR3D - RNA polymerase III subunit D Gene

Also Known as C53; RPC4; BN51T; RPC53; TSBN51

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 661

About POLR3D

Cytogenetic location: 8p21.3 Genomic coordinates (GRCh38): 8:22,245,133-22,254,601 (from NCBI)

This gene has 5 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in testis (RPKM 12.6), placenta (RPKM 8.6) and 25 other tissues.

Summary

This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures. [provided by RefSeq, Jul 2008]

POLR3D Products (1)

mRNA Protein Name
NM_001722.3 NP_001713.2 DNA-directed RNA polymerase III subunit RPC4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables chromatin binding IDA
IDA: Inferred from direct assay
24107381 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in positive regulation of innate immune response IDA
IDA: Inferred from direct assay
19631370 GOA
involved in positive regulation of interferon-beta production IDA
IDA: Inferred from direct assay
19631370 GOA
Cellular Component GO Annotation Evidence Verweise Source
part of RNA polymerase III complex IDA
IDA: Inferred from direct assay
24107381 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

POLR3D Protein Structure

RNA_pol_Rpc4

RNA_pol_Rpc4: RNA polymerase III RPC4 (263 - 389)

  • 0
  • 100
  • 200
  • 300
  • 398 a.a.
Protein Preferred Names Protein Names

DNA-directed RNA polymerase III subunit RPC4

  • BN51 (BHK21) temperature sensitivity complementing

Related Diseases

Diseases Alias
Lipoid Congenital Adrenal Hyperplasia

  • Congenital Adrenal Hyperplasia

  • Congenital Lipoid Adrenal Hyperplasia Due To Star Deficency

  • Congenital Lipoid Adrenal Hyperplasia

  • Lipoid Cah

  • Lipoid Adrenal Hyperplasia

  • Adrenal Hyperplasia 1

  • Cah

  • Clah

  • LCAH

  • Adrenal Hyperplasia I

  • Lipoid Hyperplasia, Congenital, Of Adrenal Cortex With Male Pseudohermaphroditism

  • Congenital Adrenal Hyperplasia Lipoid

  • Adrenal Hyperplasia, Congenital

  • Congenital Adrenal Hyperplasia, Lipoid

  • AH1

  • Congenital Lipoid Hyperplasia Of Adrenal Cortex With Male Pseudohermaphroditism

  • Adrenal Hyperplasia Congenital

  • Hyperplasia, Adrenal, Lipoid, Congenital

  • Congenital Adrenogenital Disorders Associated With Enzyme Deficiency

  • Congenital Adrenal Cortical Hyperplasia

  • Congenital Adrenal Gland Hyperplasia

  • Congenital Adrenogenital Syndrome

  • Congenital Hyperadrenocorticism

  • Congenital Adrenogenitalism

  • Congenital Female Adrenal Pseudohermaphroditism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS10858 POLR3D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta POLR3D VGNC VGNC:76017
Felis catus POLR3D VGNC VGNC:64292
Bos taurus POLR3D VGNC VGNC:33148
Mus musculus POLR3D MGD MGI:1914315
Canis familiaris POLR3D VGNC VGNC:44803
Rattus norvegicus POLR3D RGD RGD:1311816
Others POLR3D NCBI