(S)-Thalidomide-5-OH
(S)-Thalidomide-5-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (S)-Thalidomide-5-OH can be linked to a target protein ligand via a linker to form a PROTAC.
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- CAS. Nr.: 172333-29-8
- Formel: C13H10N2O5
- Molecular Weight:274.23
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 172333-29-8
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Molecular Weight 274.23
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Formel C13H10N2O5
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SMILES
O=C1N(C(=O)C=2C1=CC(O)=CC2)[C@@H]3C(=O)NC(=O)CC3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)