172333-29-8
172333-29-8
Chemical Structure
(S)-Thalidomide-5-OH
- CAS No.: 172333-29-8
- Formula:C13H10N2O5
- Molecular Weight:274.23
IUPAC Name: (S)-2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione
InChIKey: LJBQRRQTZUJWRC-VIFPVBQESA-N
SMILES: O=C1N(C(=O)C=2C1=CC(O)=CC2)[C@@H]3C(=O)NC(=O)CC3
Biological Activity: (S)-Thalidomide-5-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (S)-Thalidomide-5-OH can be linked to a target protein ligand via a linker to form a PROTAC.
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(S)-Thalidomide-5-OH | (S)-Thalidomide-5-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (S)-Thalidomide-5-OH can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
