USP1-IN-13
USP1-IN-13 (Compound 2) is a potent and orally active USP1 inhibitor with an IC50 value of 1.02 nM. USP1-IN-13 can be used for the study of breast cancer.
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- CAS. Nr.: 2974433-50-4
- Formel: C30H33F4N7O
- Molecular Weight:583.62
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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USP1 1.02 nM (IC50) |
USP1-IN-13 (Compound 2) (14 d) inhibits the colony-forming ability of MDA-MB-436 cells, with its IC50 value being 31.34 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| Species | Dose | Route | Cmax | AUC0-t |
|---|---|---|---|---|
| Mice[1] | 10 mg/kg | i.g. | 1432 ng/mL | 9888 ng·h/mL |
Chemical Information
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CAS. Nr. 2974433-50-4
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Molecular Weight 583.62
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Formel C30H33F4N7O
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SMILES
COC1=C(C(C2CC2)=NC=N1)C3=C(C4=C(C=NN4CC56CCC(CC5)(CC6)C7=NC(C(F)(F)F)=CN7C(C)C)C=N3)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
USP1-IN-13 Related Classifications
HY-176704 Related Classifications
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