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Cat. No.: HY-187352

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5-HT2A agonist-11

5-HT2A agonist-11 (Compound S82) is a 5-HT2A receptor agonist with an EC₅₀ of 1.5 nM. 5-HT2A agonist-11 can be used for the research of central nervous system diseases.

For research use only. We do not sell to patients.

Formula: C₁₅H₁₉N₃O
Molecular Weight:257.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

5-HT2A agonist-11 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

5-HT2A agonist-11 (Compound S82) is a 5-HT2A receptor agonist with an EC₅₀ of 1.5 nM. 5-HT2A agonist-11 can be used for the research of central nervous system diseases^[1].

IC₅₀ & Target^[1]

5-HT_2A Receptor

1.5 nM (EC₅₀)

All 5-HT Receptor Isoforms :

In Vitro

5-HT2A agonist-11 functionally activates the 5-HT2A receptor in Ca²⁺ flux functional assays^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 257.33
Formula C₁₅H₁₉N₃O
SMILES

COC1=CC=C(NC=C2CCN3[C@H]4[C@H](C4)CC3)C2=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sabnis RW, et al. Novel Compounds as 5‑HT2A Agonists for Treating Mental Illness or CNS Disorders. ACS medicinal chemistry letters. 2025 Sep 11;16(9):1711-1712. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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5-HT2A agonist-11

All 5-HT Receptor Isoforms