2408994-22-7
2408994-22-7
Chemical Structure
BET-IN-15
- CAS No.: 2408994-22-7
- Formula:C21H18F2N4O3S
- Molecular Weight:444.45
InChIKey: YDEQUCDDNAFAGR-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C3=C(OC4=CC=C(C=C4F)F)C=CC(N=S(C)(C)=O)=N3)=CN1C)C=CN2
Biological Activity: BET-IN-15 (compound 1) is a potent and orally active BET inhibitor with IC50 values of 0.64，0.25 nM for BRD4-BD1，BRD4-BD2，respectively. BET-IN-15 shows antiproliferative activity[1].
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BET-IN-15 | BET-IN-15 (compound 1) is a potent and orally active BET inhibitor with IC50 values of 0.64，0.25 nM for BRD4-BD1，BRD4-BD2，respectively. BET-IN-15 shows antiproliferative activity. | |||||||||||||||||||||
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References
Keywords
