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Norepinephrine hydrochloride

(Synonyms: Levarterenol hydrochloride; L-Noradrenaline hydrochloride)
62 Cited Publications
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Based on 62 publication(s) in Google Scholar

Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors.

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  • Pureté: 99.45%
  • CAS No.: 329-56-6
  • Formule: C8H12ClNO3
  • Masse moléculaire:205.64
  • Stockage:

    4°C, stored under nitrogen, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

  • Norepinephrine hydrochloride Chemical Structure
    Norepinephrine hydrochloride Chemical Structure
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
  • Experimental Validation Results for Norepinephrine hydrochloride
CAS No.: 329-56-6
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  • Norepinephrine hydrochloride Chemical Structure
    Norepinephrine hydrochloride Chemical Structure
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    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Cell. 2026 Mar 5;189(5):1323-1340.e25. [Abstract]

    Customer Validation
     Norepinephrine bitartrate monohydrate (NE) (0.5 mM; 12 h) decreased CXCL16 level in mouse and human cultured keratinocytes.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Cell. 2026 Mar 5;189(5):1323-1340.e25. [Abstract]

    Customer Validation
     Norepinephrine bitartrate monohydrate (NE) (2 mM; 100 μL; i.d.) caused a pronounced decrease in keratinocyte CXCL16 expression in C57BL/6J mice.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Cell. 2026 Mar 5;189(5):1323-1340.e25. [Abstract]

    Customer Validation
     Norepinephrine bitartrate monohydrate (NE) (0.5 mM; 12 h) decreased Cxcl16 and Tgfb3 expression in cultured mouse keratinocytes.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Cell. 2026 Mar 5;189(5):1323-1340.e25. [Abstract]

    Customer Validation
     Norepinephrine bitartrate monohydrate (NE) (2 mM; 100 μL; i.d.) led to a significant reduction of skin CD8+ TRM cells in C57BL/6J mice.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Cell. 2026 Mar 5;189(5):1323-1340.e25. [Abstract]

    Customer Validation
     Norepinephrine bitartrate monohydrate (NE) (0.5 mM; 12 h) decreased Cxcl16 and Tgfb3 expression in cultured human keratinocytes.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Atenolol (ATN, 1 µM, 72 h) rescued the Norepinephrine (NE, 10 µM)-induced decrease in TM4 cell viability.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Atenolol (ATN, 1 µM, 48 h) restored the Norepinephrine (NE, 10 µM)-induced increase in intracellular ferrous ion concentration in TM4 cells.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Atenolol (ATN, 1 µM, 48 h) restored the Norepinephrine (NE, 10 µM)-induced decrease in mitochondrial membrane potential in TM4 cells.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Atenolol (ATN, 1 µM, 48 h) reversed Norepinephrine (NE,10 μM）-induced alterations in the expression of SLC7A11, GPX4, and ACSL4 in TM4 cells.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Atenolol (ATN, 1 µM, 48 h) reversed Norepinephrine (NE,10 μM）-induced alterations in the expression of SLC7A11, GPX4, and ACSL4 in TM4 cells.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 May 7;15(1):3834. [Abstract]

    Customer Validation
     Representative images of DLAT oligomer immunofluorescence imaging by confocal microscopy. Scale bar = 20 μm. HL-1 cells were treated with 10 µM CuCl2 in the presence of solvent (DMSO), 1 µM NE or 10 µM NE for 24 h.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Mol Immunol. 2023 Feb;20(2):175-188. [Abstract]

    Customer Validation
     Effects of epinephrine (EPI) and norepinephrine (NE) on virus-induced transcription of antiviral genes. THP1 cells (1 × 106) were treated with EPI or NE (10 μM) and then uninfected or infected with SeV or HSV-1 (MOI = 1), and at the indicated times, qPCR analysis was performed to determine the levels of the indicated mRNAs.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Mol Immunol. 2023 Feb;20(2):175-188. [Abstract]

    Customer Validation
     Effects of EPI/NE/isoprenaline (ISO) on virus-induced transcription of antiviral genes. THP1 cells (1 × 106) were treated with EPI, NE or ISO (10 μM) and uninfected or infected with EMCV (MOI = 1). Ten hours later, qPCR analysis was performed to determine the levels of the indicated mRNAs.

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: Cardiovasc Res. 2018 Feb 1;114(2):300-311. [Abstract]

    Customer Validation
     Knockdown of GATA4 ameliorated morphology and functional changes in a Meox1 cell line with NE stimulation. Immunodetection of actin in HL-1 cells. Actin staining appeared green, and sections are counterstained blue with DAPI (40,6-diamidino-2-phenylindole).

  • 1/16

    Norepinephrine hydrochloride purchased from MedChemExpress. Usage Cited in: J Nutr Biochem. 2018 Aug:58:110-118. [Abstract]

    Customer Validation
     PASMCs are pretreated with or not Norepinephrine (50 μM) or ICI 118,551 (5 nM), and α-SMA (D) are analyzed.

  • Norepinephrine hydrochloride