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Cat. No.: HY-126311

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4-Hydroxyresveratrol

(Synonyms: 3,4,5,4'-Tetrahydroxystibene)

4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene), a Resveratrol (HY-16561) analog, differentially induces pro-apoptotic p53/Bax gene expression. 4-Hydroxyresveratrol induces apoptosis in SV40 virally transformed WI38 cells (WI38VA) cells, but not in WI38 cells. 4-Hydroxyresveratrol significantly induces the expression of p53, GADD45 and Bax genes and concomitantly suppresses the expression of bcl-2 gene in WI38VA.

For research use only. We do not sell to patients.

CAS No.: 331443-00-6
Formula: C₁₄H₁₂O₄
Molecular Weight:244.24

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

4-Hydroxyresveratrol Chemical Structure

CAS No.: 331443-00-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Biological Activity

Description

IC₅₀ & Target^[1]

Bax

All Bcl-2 Family Isoforms :

Chemical Information

CAS No. 331443-00-6
Molecular Weight 244.24
Formula C₁₄H₁₂O₄
SMILES

OC1=CC(/C=C/C2=CC=C(O)C=C2)=CC(O)=C1O
Synonyms

3,4,5,4'-Tetrahydroxystibene
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. J Lu, et al. Resveratrol analog, 3,4,5,4'-tetrahydroxystilbene, differentially induces pro-apoptotic p53/Bax gene expression and inhibits the growth of transformed cells but not their normal counterparts. Carcinogenesis. 2001 Feb;22(2):321-8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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4-Hydroxyresveratrol

All Bcl-2 Family Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

4-Hydroxyresveratrol Related Classifications

HY-126311 Related Classifications