ELQ-316
ELQ-316 is an endochinlike quinolone compound and an anti-parasite agent. ELQ-316 demonstrates a great efficacy against acute and chronic experimental toxoplasmosis.
For research use only. We do not sell to patients.
- CAS No.: 1354745-69-9
- Formula: C24H17F4NO4
- Molecular Weight:459.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>10 μM
Compound: 18b, ELQ-316
|
Inhibition of human cytochrome bc1 complex derived from HEK293 cell mitochondria using 50 uM decylubiquinol as substrate
Inhibition of human cytochrome bc1 complex derived from HEK293 cell mitochondria using 50 uM decylubiquinol as substrate
|
[PMID: 24720377] |
| HepG2 | IC50 |
>10 μM
Compound: 18b, ELQ-316
|
Cytotoxicity against human HepG2 cells after 24 hrs incubation by Alamar Blue assay
Cytotoxicity against human HepG2 cells after 24 hrs incubation by Alamar Blue assay
|
[PMID: 24720377] |
Chemical Information
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CAS No. 1354745-69-9
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Molecular Weight 459.39
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Formula C24H17F4NO4
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SMILES
O=C1C2=CC(F)=C(C=C2NC(C)=C1C3=CC=C(OC4=CC=C(C=C4)OC(F)(F)F)C=C3)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)