LHQ766
LHQ766 is a highly selective, orally active, covalent FGFR2 inhibitor with an IC50 of 7.3 nM. LHQ766 significantly suppresses phosphorylation of FGFR2 and its downstream signaling molecules FRS2-a, Akt and ERK1/2. LHQ766 selectively suppresses the proliferation of FGFR2-driven cancer cells.
For research use only. We do not sell to patients.
- Formula: C28H27F2N5O3
- Molecular Weight:519.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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FGFR2 7.3 nM (IC50) |
ERK1 |
ERK2 |
Chemical Information
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Molecular Weight 519.54
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Formula C28H27F2N5O3
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SMILES
CC(C=C1NC(C(F)=C)=O)=C(C=C1)C2=C(C3=C(N=CN=C3N2C)N)C4=CC(F)=C(C=C4)C5(COC5)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LHQ766 Related Classifications
HY-180794 Related Classifications
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