DSR-71167
DSR-71167 is an orally active mineralocorticoid receptor (MR) antagonist with an IC50 of 0.26 μM. DSR-71167 exhibits weak carbonic anhydrase (CA) inhibitory activity with an IC50 of 19 μM. DSR-71167 can dose-dependently increase urinary sodium excretion in rat models and has a very low risk of hyperkalemia in potassium-loading rat models. DSR-71167 lowers systolic blood pressure in hypertensive rat models. DSR-71167 can be used for research on hypertension and heart failure.
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- CAS No.: 1355687-91-0
- Formule: C23H23ClF3N3O4S
- Masse moléculaire:529.96
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 1355687-91-0
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Masse moléculaire 529.96
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Formule C23H23ClF3N3O4S
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SMILES
O=C(C1=CC=C(C2=CC=CC=C2F)C(CNCC(F)F)=C1)NC3=CC=C(S(=O)(N)=O)C(OC)=C3.Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSR-71167 Related Classifications
HY-120321 Related Classifications
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