Shroom3 - shroom family member 3 Gene

Also Known as Shrm; Shrm3; D5Ertd287e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27428

Summary

Enables actin binding activity. Acts upstream of or within several processes, including columnar/cuboidal epithelial cell development; neural tube closure; and regulation of cell shape. Located in several cellular components, including adherens junction; apical junction complex; and apical plasma membrane. Is expressed in several structures, including central nervous system; gut; paraxial mesenchyme; sensory organ; and skeletal musculature. Orthologous to human SHROOM3 (shroom family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Shroom3 Products (3)

mRNA Protein Name
NM_001077595.2 NP_001071063.1 protein Shroom3 isoform 2
NM_001077596.2 NP_001071064.1 protein Shroom3 isoform 2
NM_015756.2 NP_056571.2 protein Shroom3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
10589677 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin cytoskeleton organization IGI
IGI: Inferred from genetic interaction
16249236 MGI
acts upstream of or within columnar/cuboidal epithelial cell development IDA
IDA: Inferred from direct assay
16249236 MGI
acts upstream of or within neural tube closure IMP
IMP: Inferred from mutant phenotype
16249236 MGI
acts upstream of or within pattern specification process IMP
IMP: Inferred from mutant phenotype
10589677 MGI
acts upstream of or within regulation of cell shape IDA
IDA: Inferred from direct assay
16249236 MGI
Cellular Component GO Annotation Evidence References Source
located in adherens junction IDA
IDA: Inferred from direct assay
10589677 MGI
located in apical junction complex IDA
IDA: Inferred from direct assay
16249236 MGI
located in apical part of cell IDA
IDA: Inferred from direct assay
16249236 MGI
located in apical plasma membrane IDA
IDA: Inferred from direct assay
15037549 MGI
located in cytoskeleton IDA
IDA: Inferred from direct assay
10589677 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Shroom3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12886 SHROOM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shroom3 NCBI NCBI:57619