FBXO43 - F-box protein 43 Gene

Also Known as EMI2; ERP1; FBX43; OOMD12; SPGF64; OZEMA12

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 286151

Summary

Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through Other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

FBXO43 Products (1)

mRNA Protein Name
XM_011516990.2 XP_011515292.1 F-box only protein 43 isoform X2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Referencias Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Referencias Source
involved in negative regulation of cell cycle process IMP
IMP: Inferred from mutant phenotype
34052850 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box only protein 43

  • early mitotic inhibitor 2

  • endogenous meiotic inhibitor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS04801 FBXO3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04806 FBXO4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04807 FBXO40 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04808 FBXO42 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04809 FBXO44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04810 FBXO47 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18517 Fbxo4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21127 Fbxo44 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24999 Fbxo4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27645 Fbxo44 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown