Δ7-Avenasterol
Based on 1 Customer Validation
Δ7-Avenasterol (Delta-7-avenasterol) is a phytosterol that binds to prostaglandin E2 receptor (prostaglandin E2 receptor) and cyclooxygenase-2 (COX-2). Δ7-Avenasterol is applicable to research related to gastric ulcer, anti-inflammation and antioxidation.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 95.0%
- No. CAS: 7212-91-1
- Fòrmula: C29H48O
- Peso molecular:412.69
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
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COX-2 |
Δ7-Avenasterol binds to the prostaglandin E2 receptor (PDB ID: 6M9T) via hydrogen bonding and hydrophobic interactions, with a docking score of -9.181 kcal/mol, indicating its potential to modulate this receptor[1].
Δ7-Avenasterol potently binds to human COX-2 enzyme with a binding affinity of -10.7 kcal/mol[2].
Δ7-Avenasterol (24-120 h) remains stable during a 5-day in vitro dynamic colonic fermentation with human fecal microbiota in two matrices: whole-grain rye bread and phytosterol-enriched whole-grain rye bread; in the whole-grain rye bread treatment group, an increase in its level in specific colonic segments is observed over time[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 7212-91-1
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Appearance Solid
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Peso molecular 412.69
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Fòrmula C29H48O
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Color White to off-white
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC/C(C(C)C)=C/C)([H])C3=CC[C@](C[C@H](CC4)O)([H])[C@@]4(C)[C@@]3([H])CC1
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Synonyms
Delta-7-avenasterol
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Adebayo-Gege G, et al. Molecular docking and anti-ulcerative potential of Cucumis (L. Inodorous) on ibuprofen induced gastric ulceration in male wistar animals. Biomed Pharmacother. 2023;161:114531. [Content Brief]
[2]. Afroz M, et al. A systematic review on antioxidant and antiinflammatory activity of Sesame (Sesamum indicum L.) oil and further confirmation of antiinflammatory activity by chemical profiling and molecular docking. Phytother Res. 2019;33(10):2585-2608. [Content Brief]
[3]. Faubel N, et al. Modulation of microbiota composition and markers of gut health after in vitro dynamic colonic fermentation of plant sterol-enriched wholemeal rye bread. Food Res Int. 2025;201:115570. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Δ7-Avenasterol Related Classifications
HY-165131 Related Classifications
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