Acetazolamide-d3
Based on 1 Customer Validation
Acetazolamide-d3 is deuterium labeled Acetazolamide (HY-B0782). Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. Acetazolamide has diuretic, antihypertensive and anti-gonococcal activities.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.9%
- No. CAS: 1189904-01-5
- Fòrmula: C4H3D3N4O3S2
- Peso molecular:225.26
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
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Help & FAQs
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 1189904-01-5
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Unlabeled Cas 59-66-5
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Appearance Solid
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Peso molecular 225.26
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Fòrmula C4H3D3N4O3S2
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Color White to off-white
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SMILES
O=C(C([2H])([2H])[2H])NC1=NN=C(S(N)(=O)=O)S1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 50 mg/mL (221.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 0.1 mg/mL (0.44 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (244 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.4393 mL | 22.1966 mL | 44.3931 mL | 110.9829 mL |
| 5 mM | 0.8879 mL | 4.4393 mL | 8.8786 mL | 22.1966 mL | |
| 10 mM | 0.4439 mL | 2.2197 mL | 4.4393 mL | 11.0983 mL | |
| 15 mM | 0.2960 mL | 1.4798 mL | 2.9595 mL | 7.3989 mL | |
| 20 mM | 0.2220 mL | 1.1098 mL | 2.2197 mL | 5.5491 mL | |
| 25 mM | 0.1776 mL | 0.8879 mL | 1.7757 mL | 4.4393 mL | |
| 30 mM | 0.1480 mL | 0.7399 mL | 1.4798 mL | 3.6994 mL | |
| 40 mM | 0.1110 mL | 0.5549 mL | 1.1098 mL | 2.7746 mL | |
| 50 mM | 0.0888 mL | 0.4439 mL | 0.8879 mL | 2.2197 mL | |
| 60 mM | 0.0740 mL | 0.3699 mL | 0.7399 mL | 1.8497 mL | |
| 80 mM | 0.0555 mL | 0.2775 mL | 0.5549 mL | 1.3873 mL | |
| 100 mM | 0.0444 mL | 0.2220 mL | 0.4439 mL | 1.1098 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Acetazolamide-d3 Related Classifications
HY-B0782S Related Classifications
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