IZUMO3 - IZUMO family member 3 Gene

Also Known as C9orf134; bA20A20.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100129669

About IZUMO3

Cytogenetic location: 9p21.3 Genomic coordinates (GRCh38): 9:24,542,952-24,545,897 (from NCBI)

This gene has 3 transcripts (splice variants) and 83 orthologues. Restricted expression toward testis (RPKM 4.9).

Summary

Predicted to enable protein homodimerization activity. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

IZUMO3 Products (2)

mRNA Protein Name
NM_001271706.1 NP_001258635.1 izumo sperm-egg fusion protein 3 isoform 1 precursor
NM_001365008.2 NP_001351937.1 izumo sperm-egg fusion protein 3 isoform 2 precursor

IZUMO3 Protein Structure

IZUMO

IZUMO: Izumo sperm-egg fusion, Ig domain-associated (16 - 173)

  • 0
  • 100
  • 200
  • 239 a.a.
Protein Preferred Names Protein Names

izumo sperm-egg fusion protein 3

Related Diseases

Diseases Alias
Calvarial Doughnut Lesions With Bone Fragility

  • Calvarial Doughnut Lesions With Bone Fragility With Or Without Spondylometaphyseal Dysplasia

  • Calvarial Doughnut Lesions-Bone Fragility Syndrome

  • CDL

  • Doughnut Lesions Of Skull, Familial

  • Calvarial Doughnut Lesions With Bone Fragility And Spondylometaphyseal Dysplasia

  • Familial Doughnut Lesions Of Skull

  • CDLSMD
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07007 IZUMO3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus IZUMO3 MGD MGI:1916564
Felis catus IZUMO3 VGNC VGNC:62993
Canis familiaris IZUMO3 VGNC VGNC:42167
Bos taurus IZUMO3 VGNC VGNC:30356
Rattus norvegicus IZUMO3 RGD RGD:2324467
Others IZUMO3 NCBI