Tmem64 - transmembrane protein 64 Gene

Also Known as 9630015D15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100201

Summary

Involved in negative regulation of canonical Wnt signaling pathway; negative regulation of osteoblast differentiation; and positive regulation of fat cell differentiation. Acts upstream of or within several processes, including positive regulation of bone resorption; positive regulation of osteoclast differentiation; and regulation of ATPase activity. Located in endoplasmic reticulum. Is expressed in several structures, including brain; head mesenchyme; retina nuclear layer; thymus primordium; and vibrissa. Orthologous to human TMEM64 (transmembrane protein 64). [provided by Alliance of Genome Resources, Apr 2022]

Tmem64 Products (1)

mRNA Protein Name
NM_181401.3 NP_852066.2 transmembrane protein 64

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23395171 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
25979161 MGI
involved in negative regulation of osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
25979161 MGI
acts upstream of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
23395171 MGI
acts upstream of or within positive regulation of bone resorption IMP
IMP: Inferred from mutant phenotype
23395171 MGI
involved in positive regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
25979161 MGI
acts upstream of or within positive regulation of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
23395171 MGI
acts upstream of or within regulation of ATP-dependent activity IMP
IMP: Inferred from mutant phenotype
23395171 MGI
acts upstream of or within regulation of cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
23395171 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
23395171 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 64

  • CG11367 gene product

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14735 TMEM64 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem64 NCBI NCBI:169200