Brk1 - BRICK1, SCAR/WAVE actin-nucleating complex subunit Gene

Also Known as 6720456B07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 101314

Summary

Predicted to enable identical protein binding activity. Predicted to contribute to small GTPase binding activity. Acts upstream of or within several processes, including actin Cytoskeleton organization; in utero embryonic development; and positive regulation of cell population proliferation. Located in lamellipodium. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; lung; and nervous system. Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex). [provided by Alliance of Genome Resources, Apr 2022]

Brk1 Products (1)

mRNA Protein Name
NM_133937.1 NP_598698.1 protein BRICK1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
20861187 MGI
acts upstream of or within cell motility IMP
IMP: Inferred from mutant phenotype
20861187 MGI
acts upstream of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
20861187 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
20861187 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
20861187 MGI
Cellular Component GO Annotation Evidence References Source
located in lamellipodium IDA
IDA: Inferred from direct assay
18560548 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein BRICK1

  • probable protein BRICK1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01625 BRK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brk1 NCBI NCBI:55845