2. Gene
  3. Hsd3b7 - hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Gene

Hsd3b7 - hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 101502 | Gene type: protein coding

About Hsd3b7

Summary

Enables cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity. Involved in B cell chemotaxis. Predicted to be located in intracellular membrane-bounded organelle and lipid droplet. Is expressed in several structures, including alimentary system; bladder; facial bone primordium; heart; and liver and biliary system. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 1 and intrahepatic cholestasis. Orthologous to human HSD3B7 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7). [provided by Alliance of Genome Resources, Apr 2022]

Hsd3b7 Products(2)

mRNA Protein Name
NM_001040684.2 NP_001035774.1 3 beta-hydroxysteroid dehydrogenase type 7 isoform b
NM_133943.3 NP_598704.2 3 beta-hydroxysteroid dehydrogenase type 7 isoform a
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity IMP
IMP: Inferred from mutant phenotype
22999953 MGI
Biological Process GO Annotation Evidence Reference Source
involved in B cell chemotaxis IMP
IMP: Inferred from mutant phenotype
22999953 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3 beta-hydroxysteroid dehydrogenase type 7

3 beta-hydroxysteroid dehydrogenase type VII

3-beta-HSD VII

3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase

c(27) 3-beta-HSD

cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06403 HSD3B7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd3b7 NCBI NCBI:80270