PAK3 - p21 (RAC1) activated kinase 3 Gene
Species: Macaca fascicularis
Gene Type: protein coding
Gene ID: 101866329
About PAK3
Primary_assembly X: 104,325,899-104,608,345 forward strand.Macaca_fascicularis_6.0:CM021959.1
This gene has 5 transcripts (splice variants), 213 orthologues and 34 paralogues.
PAK3 Products (19)
| mRNA | Protein | Name |
|---|---|---|
| XM_045383862.1 | XP_045239797.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383868.1 | XP_045239803.1 | serine/threonine-protein kinase PAK 3 isoform X3 |
| XM_005594377.3 | XP_005594434.1 | serine/threonine-protein kinase PAK 3 isoform X4 |
| XM_045383857.1 | XP_045239792.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383858.1 | XP_045239793.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383864.1 | XP_045239799.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_005594373.3 | XP_005594430.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_005594376.3 | XP_005594433.1 | serine/threonine-protein kinase PAK 3 isoform X4 |
| XM_045383863.1 | XP_045239798.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383861.1 | XP_045239796.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383866.1 | XP_045239801.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383856.1 | XP_045239791.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383867.1 | XP_045239802.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_005594375.3 | XP_005594432.1 | serine/threonine-protein kinase PAK 3 isoform X3 |
| XM_045383859.1 | XP_045239794.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383865.1 | XP_045239800.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_045383854.1 | XP_045239789.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
| XM_005594374.3 | XP_005594431.1 | serine/threonine-protein kinase PAK 3 isoform X2 |
| XM_045383855.1 | XP_045239790.1 | serine/threonine-protein kinase PAK 3 isoform X1 |
PAK3 Protein Structure
PBD
PBD: pfam00786 (68 - 140)
STKc_PAK_I
STKc_PAK_I: cd06647 (274 - 529)
- 0
- 100
- 200
- 300
- 400
- 500
- 562 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
serine/threonine-protein kinase PAK 3 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-13007 | PF-3758309 | Inhibitor | 99.79% | Phase 1 |
| HY-13007A | PF-3758309 hydrochloride | Inhibitor | / | Phase 1 |
| HY-13007B | PF-3758309 dihydrochloride | Inhibitor | / | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(7)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-15542A | FRAX597 | Inhibitor | 99.36% | Unkown |
| HY-15542B | FRAX486 | Inhibitor | 98.10% | Unkown |
| HY-123739 | LDN-0028574 | Inhibitor | / | Unkown |
| HY-146786 | ZMF-10 | Inhibitor | / | Unkown |
| HY-178812 | PI3Kα-IN-27 | Inhibitor | / | Unkown |
| HY-184447 | RN193 | Inhibitor | / | Unkown |
| HY-118606 | LDN-0044878 | Inhibitor | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service