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Cat. No.: HY-123739

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LDN-0028574

LDN-0028574 is a PAK3 inhibitor. LDN-0028574 can be used in the research of p53-deficient cancers.

For research use only. We do not sell to patients.

CAS No.: 337500-87-5
Formula: C₂₁H₁₄N₄O₄S
Molecular Weight:418.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

LDN-0028574 Chemical Structure

CAS No.: 337500-87-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

LDN-0028574 is a PAK3 inhibitor. LDN-0028574 can be used in the research of p53-deficient cancers^[1].

IC₅₀ & Target^[1]

PAK3

All PAK Isoforms :

In Vitro

LDN-0028574 (10 μM) inhibits PAK3 kinase activity by 91% at a concentration of 10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 337500-87-5
Molecular Weight 418.43
Formula C₂₁H₁₄N₄O₄S
SMILES

N#CC1=C(N=C(N)C(C#N)=C1C=2C=CC(O)=CC2)SCC(=O)C3=CC=C(O)C(O)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Amy Baldwin, et al. Compositions and method for inhibiting tumor growth. WO2010141738A2.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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LDN-0028574

All PAK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

LDN-0028574 Related Classifications

HY-123739 Related Classifications