Nup107 - nucleoporin 107 Gene

About Nup107

Summary

Predicted to be a structural constituent of nuclear pore. Predicted to be involved in several processes, including nuclear pore complex assembly; nucleocytoplasmic transport; and posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in nuclear membrane and nuclear periphery. Predicted to be part of nuclear pore outer ring. Predicted to colocalize with kinetochore. Is expressed in embryo and neural tube. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome; nephrotic syndrome type 11; and ovarian dysgenesis 6. Orthologous to human NUP107 (nucleoporin 107). [provided by Alliance of Genome Resources, Apr 2022]