Mgat4b - mannoside acetylglucosaminyltransferase 4, isoenzyme B Gene

Also Known as GnTIVb

Species: Mus musculus

Gene Type: protein coding
Gene ID: 103534

Summary

Enables acetylglucosaminyltransferase activity. Acts upstream of or within protein N-linked glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi stack; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including adrenal gland; nervous system; nose; respiratory system; and urinary system. Orthologous to human MGAT4B (alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B). [provided by Alliance of Genome Resources, Apr 2022]

Mgat4b Products (1)

mRNA Protein Name
NM_145926.3 NP_666038.3 alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acetylglucosaminyltransferase activity IDA
IDA: Inferred from direct assay
20015870 MGI
enables glycosyltransferase activity IDA
IDA: Inferred from direct assay
24619415 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein N-linked glycosylation IGI
IGI: Inferred from genetic interaction
20015870 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

  • GlcNAc-T IVb

  • N-acetylglucosaminyltransferase IVb

  • N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb

  • UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb

  • gnT-IVb

  • mannosyl (alpha-1,3-)-gly

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70286 N-Acetylglucosaminyltransferase V / Unkown
HY-RS08405 MGAT4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mgat4b NCBI NCBI:11282