2. Gene
  3. RFWD3 - Rfwd3 ring finger and WD repeat domain 3 Gene

RFWD3 - Rfwd3 ring finger and WD repeat domain 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1305243

Gene ID: 103690025 | Gene type: protein coding

About RFWD3

Summary

Predicted to enable MDM2/MDM4 family protein binding activity; p53 binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including DNA metabolic process; regulation of cell cycle phase transition; and response to ionizing radiation. Predicted to be located in nucleoplasm and site of DNA damage. Predicted to colocalize with site of double-strand break. Human ortholog(s) of this gene implicated in Fanconi anemia. Orthologous to human RFWD3 (ring finger and WD repeat domain 3). [provided by Alliance of Genome Resources, Apr 2022]

RFWD3 Products(2)

mRNA Protein Name
NM_001402201.1 NP_001389130.1 ring finger and WD repeat domain 3 isoform 1
NM_001402202.1 NP_001389131.1 ring finger and WD repeat domain 3 isoform 2
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RFWD3

ring finger and WD repeat domain 3

E3 ubiquitin-protein ligase RFWD3-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11878 RFWD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens RFWD3 NCBI NCBI:55159