RFWD3 - Rfwd3 ring finger and WD repeat domain 3 Gene
Also Known as RGD1305243
Species: Rattus norvegicus
Summary
Predicted to enable MDM2/MDM4 family protein binding activity; p53 binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including DNA metabolic process; regulation of cell cycle phase transition; and response to ionizing radiation. Predicted to be located in nucleoplasm and site of DNA damage. Predicted to colocalize with site of double-strand break. Human ortholog(s) of this gene implicated in Fanconi anemia. Orthologous to human RFWD3 (ring finger and WD repeat domain 3). [provided by Alliance of Genome Resources, Apr 2022]
RFWD3 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001402201.1 | NP_001389130.1 | ring finger and WD repeat domain 3 isoform 1 |
| NM_001402202.1 | NP_001389131.1 | ring finger and WD repeat domain 3 isoform 2 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
E3 ubiquitin-protein ligase RFWD3 ring finger and WD repeat domain 3 |
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