MYCNOS - MYCN opposite strand Gene

Also Known as NCYM; NYCM; N-CYM; MYCN-AS1

Species: Homo sapiens

Gene Type: ncRNA
Gene ID: 10408

About MYCNOS

Cytogenetic location: 2p24.3 Genomic coordinates (GRCh38): 2:15,936,265-15,942,433 (from NCBI)

This gene has 5 transcripts (splice variants). Low expression observed in reference dataset.

Summary

This gene is transcribed in antisense to the v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog gene (MYCN). It is thought to encode a small, novel protein that stabilizes MYCN, prevents Apoptosis, and promotes cell proliferation. Transcripts at this locus may also act directly as functional RNAs to recruit transcriptional regulators to the promoter of MYCN and stimulate transcription of this oncogene. This gene therefore functions through both RNA and protein products. [provided by RefSeq, Aug 2016]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24391509 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of kinase activity IDA
IDA: Inferred from direct assay
24391509 GOA
involved in regulation of protein stability IMP
IMP: Inferred from mutant phenotype
24391509 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
24391509 GOA
located in nucleus IDA
IDA: Inferred from direct assay
24391509 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Diseases

Diseases Alias
Feingold Syndrome 1

  • Feingold Syndrome

  • Oculodigitoesophagoduodenal Syndrome

  • Oded Syndrome

  • Microcephaly-Oculo-Digito-Esophageal-Duodenal Syndrome

  • Digital Anomalies With Short Palpebral Fissures And Atresia Of Esophagus Or Duodenum

  • FGLDS1

  • Mmt Syndrome

  • Brunner-Winter Syndrome

  • Feingold Syndrome Type 1

  • Oded

  • Moded

  • Fglds

  • Microcephaly-Digital Anomalies-Normal Intelligence Syndrome

  • Moded Syndrome

  • Oculo-Digito-Esophageal-Duodenal Syndrome

  • Microcephaly, Mental Retardation, And Tracheoesophageal Fistula Syndrome

  • Microcephaly And Digital Abnormalities With Normal Intelligence

  • Digital Anomalies With Short Palpebral Fissures And Atresia Of Esophagus, Or Duodenum

  • Microcephaly-Mesobrachyphalangy-Tracheoesophageal Fistula Syndrome

  • Microcephaly-Oculo-Digito-Esophageal-Duodenal Syndrome

  • Oculo-Digito-Esophagoduodental Syndrome

  • Fs

  • Mmt

  • Microcephaly-Intellectual Disability-Tracheoesophageal Fistula Syndrome

  • Microcephaly-Oculo-Digito-Esophageal-Duodenal Syndrome Syndrome

  • Brunner-Winter Syndrome Type 1

  • Digital Anomalies With Short Palpebral Fissures And Atresia Of Esophagus Or Duodenum Type 1

  • Fs1

  • Mmt Type 1

  • Moded Syndrome Type 1

  • Microcephaly-Digital Anomalies-Normal Intelligence Syndrome Type 1

  • Microcephaly-Intellectual Disability-Tracheoesophageal Fistula Syndrome Type 1

  • Microcephaly-Oculo-Digito-Esophageal-Duodenal Syndrome Syndrome Type 1

  • Oded Syndrome Type 1

  • Oculo-Digito-Esophageal-Duodenal Syndrome Type 1

  • Feingold Syndrome, Type 1
Neuroblastoma

  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma
Pancreatic Adenocarcinoma

  • Adenocarcinoma Of The Pancreas

  • Adenocarcinoma Of Pancreas

  • Pancreas Adenocarcinoma

  • Malignant Exocrine Neoplasm

  • Primary Pancreatic Adenocarcinoma

  • Adenocarcinoma Of Islet Cell Of Pancreas

  • Islet Cell Adenocarcinoma Of Unspecified Site

  • Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Medulloblastoma

  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site
Gliosarcoma

  • Glioblastoma With Sarcomatous Component

  • Sarcomatous Glioblastoma
Giant Cell Glioblastoma

  • Monstrocellular Sarcoma
Glioblastoma

  • Glioblastoma Multiforme

  • Gbm

  • Adult Glioblastoma Multiforme

  • Grade Iv Adult Astrocytic Tumor

  • Primary Glioblastoma Multiforme

  • Spongioblastoma Multiforme

  • Adult Glioblastoma

  • Primary Glioblastoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma