NSA2 - NSA2 ribosome biogenesis factor Gene

Also Known as HCLG1; TINP1; CDK105; HCL-G1; HUSSY29; HUSSY-29

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10412

About NSA2

Cytogenetic location: 5q13.3 Genomic coordinates (GRCh38): 5:74,767,249-74,780,113 (from NCBI)

This gene has 5 transcripts (splice variants) and 175 orthologues. Ubiquitous expression in ovary (RPKM 71.9), lymph node (RPKM 43.0) and 25 other tissues.

Summary

This gene encodes a nucleolar protein involved in cell cycle regulation and proliferation. This gene was identified based on sequence similarity to a highly conserved Saccharomyces cerevisiae gene encoding a pre-ribosomal protein, which is involved in large ribosomal subunit biogenesis. The encoded protein is found at elevated levels in diabetic nephropathy. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified. [provided by RefSeq, Nov 2012]

NSA2 Products (3)

mRNA Protein Name
NM_001271665.2 NP_001258594.1 ribosome biogenesis protein NSA2 homolog isoform 2
NM_001364506.2 NP_001351435.1 ribosome biogenesis protein NSA2 homolog isoform 3
NM_014886.6 NP_055701.1 ribosome biogenesis protein NSA2 homolog isoform 1

NSA2 Protein Structure

Ribosomal_S8e

Ribosomal_S8e: Ribosomal protein S8e (1 - 259)

  • 0
  • 100
  • 200
  • 260 a.a.
Protein Preferred Names Protein Names

ribosome biogenesis protein NSA2 homolog

  • NSA2, ribosome biogenesis homolog

Related Diseases

Diseases Alias
Hairy Cell Leukemia

  • Hcl-V

  • Hairy Cell Leukemia Variant

  • Hairy Cell Leukaemia Variant

  • Hcl

  • Leukemic Reticuloendotheliosis

  • Leukemic Reticuloendotheliosis Variant

  • Prolymphocytic Variant Of Hcl

  • Prolymphocytic Variant Of Hairy Cell Leukemia

  • Leukemia Hairy Cell

  • Leukemia, Hairy Cell

  • Leukaemic Reticuloendotheliosis

  • Lre - [Leukemic Reticuloendotheliosis]

  • Hairy-Cell Leukaemia, Nos

  • Hcl - [Hairy Cell Leukaemia]

  • Hairy-Cell Leukaemia Without Mention Of Remission
Lateral Ventricle Meningioma

  • Meningioma Of The Lateral Ventricle
Louping Ill
Alopecia, Neurologic Defects, And Endocrinopathy Syndrome

  • Ane Syndrome

  • ANES

  • Alopecia-Progressive Neurological Defect-Endocrinopathy Syndrome

  • Alopecia-Progressive Neurological Defect-Endocrinopathy

  • Endocrine System Diseases
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09586 NSA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus NSA2 RGD RGD:621335
Mus musculus NSA2 MGD MGI:1913883
Macaca mulatta NSA2 VGNC VGNC:84455
Others NSA2 NCBI