2. Gene
  3. Spata7 - spermatogenesis associated 7 Gene

Spata7 - spermatogenesis associated 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HSD3; B230306G18Rik

Gene ID: 104871 | Gene type: protein coding

About Spata7

Summary

Involved in microtubule Cytoskeleton organization; photoreceptor cell maintenance; and protein localization to non-motile cilium. Located in photoreceptor distal connecting cilium. Is active in rod photoreceptor outer segment. Is expressed in several structures, including blood vessel; central nervous system; and retina layer. Used to study Leber congenital amaurosis 3. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 3. Orthologous to human SPATA7 (spermatogenesis associated 7). [provided by Alliance of Genome Resources, Apr 2022]

Spata7 Products(4)

mRNA Protein Name
NM_001289572.1 NP_001276501.1 spermatogenesis-associated protein 7 homolog isoform 2
NM_001289573.1 NP_001276502.1 spermatogenesis-associated protein 7 homolog isoform 3
NM_001289574.1 NP_001276503.1 spermatogenesis-associated protein 7 homolog isoform 4
NM_178914.4 NP_849245.2 spermatogenesis-associated protein 7 homolog isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
29899041 MGI
Biological Process GO Annotation Evidence Reference Source
involved in microtubule cytoskeleton organization IGI
IGI: Inferred from genetic interaction
29899041 MGI
involved in microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
29899041 MGI
involved in photoreceptor cell maintenance IMP
IMP: Inferred from mutant phenotype
25398945 MGI
involved in protein localization to photoreceptor connecting cilium IMP
IMP: Inferred from mutant phenotype
25398945 MGI
involved in protein localization to photoreceptor outer segment IMP
IMP: Inferred from mutant phenotype
25398945 MGI
Cellular Component GO Annotation Evidence Reference Source
located in photoreceptor connecting cilium IDA
IDA: Inferred from direct assay
25398945 MGI
located in photoreceptor distal connecting cilium IDA
IDA: Inferred from direct assay
29899041 MGI
is active in photoreceptor distal connecting cilium IMP
IMP: Inferred from mutant phenotype
29899041 MGI
is active in rod photoreceptor outer segment IGI
IGI: Inferred from genetic interaction
29899041 MGI
is active in rod photoreceptor outer segment IMP
IMP: Inferred from mutant phenotype
29899041 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spermatogenesis-associated protein 7 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13644 SPATA7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spata7 NCBI NCBI:55812