Lpxn - leupaxin Gene

Also Known as LDPL; 4933402K05Rik; A530083L21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107321

Summary

Enables transcription coregulator activity. Involved in negative regulation of B cell receptor signaling pathway and regulation of cell adhesion mediated by Integrin. Located in focal adhesion; nucleus; and podosome. Is expressed in bladder; epithelium of pelvic urethra of female; ovary; thymus medullary core; and ureter. Orthologous to human LPXN (leupaxin). [provided by Alliance of Genome Resources, Apr 2022]

Lpxn Products (2)

mRNA Protein Name
NM_001361971.1 NP_001348900.1 leupaxin isoform 2
NM_134152.4 NP_598913.1 leupaxin isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12674328 MGI
enables transcription coregulator activity IDA
IDA: Inferred from direct assay
18497331 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of B cell receptor signaling pathway IDA
IDA: Inferred from direct assay
17640867 MGI
involved in regulation of cell adhesion mediated by integrin IMP
IMP: Inferred from mutant phenotype
19917054 MGI
Cellular Component GO Annotation Evidence References Source
located in focal adhesion IDA
IDA: Inferred from direct assay
19917054 MGI
located in nucleus IDA
IDA: Inferred from direct assay
18497331 MGI
located in podosome IDA
IDA: Inferred from direct assay
12674328 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leupaxin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07775 LPXN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lpxn NCBI NCBI:9404