H1f6 - H1.6 linker histone, cluster member Gene

Also Known as H1t; H1-6; H1.6; H1ft; Hist1h1t

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107970

Summary

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element [provided by RefSeq, Aug 2015]

H1f6 Products (2)

mRNA Protein Name
NM_010377.3 NP_034507.2 histone H1t
NM_010377.3 NP_034507.2 histone H1t

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15562002 MGI
enables double-stranded DNA binding IMP
IMP: Inferred from mutant phenotype
16006555 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within binding of sperm to zona pellucida IGI
IGI: Inferred from genetic interaction
15685642 MGI
acts upstream of or within flagellated sperm motility IGI
IGI: Inferred from genetic interaction
15685642 MGI
acts upstream of or within spermatogenesis IGI
IGI: Inferred from genetic interaction
15051954 MGI
Cellular Component GO Annotation Evidence References Source
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
18316482 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
18283110 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone H1t

  • H1 histone family, member T (testis-specific)

  • histone 1, H1t

  • histone cluster 1, H1t

  • testicular H1 histone