Eif2b3 - eukaryotic translation initiation factor 2B, subunit 3 Gene

Mus musculus

Also known as 1190002P15Rik

Gene ID: 108067 | Gene type: protein coding

About Eif2b3

Summary

Predicted to enable guanyl-nucleotide exchange factor activity and translation initiation factor activity. Predicted to contribute to translation factor activity, RNA binding. Predicted to be involved in several processes, including T cell receptor signaling pathway; cytoplasmic translational initiation; and oligodendrocyte development. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 2B complex and guanyl-nucleotide exchange factor complex. Is expressed in central nervous system; gonad; retina; and thyroid gland. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]

Eif2b3 Products(3)

mRNA	Protein	Name
NM_001111277.2	NP_001104747.1	translation initiation factor eIF-2B subunit gamma isoform 1
NM_001355225.1	NP_001342154.1	translation initiation factor eIF-2B subunit gamma isoform 3
NM_175135.5	NP_780344.2	translation initiation factor eIF-2B subunit gamma isoform 2

Protein Preferred Names

Protein Names

translation initiation factor eIF-2B subunit gamma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04250	EIF2B3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Eif2b3	NCBI	NCBI:8891

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