Ltbp4 - latent transforming growth factor beta binding protein 4 Gene

Also Known as 2310046A13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 108075

Summary

Predicted to enable transforming growth factor beta binding activity. Involved in elastic fiber assembly. Acts upstream of or within hormone secretion and transforming growth factor beta receptor signaling pathway. Located in microfibril. Is expressed in aorta; blood vessel; ovary; and oviduct. Used to study cutis laxa. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IC. Orthologous to human LTBP4 (latent transforming growth factor beta binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Ltbp4 Products (3)

mRNA Protein Name
NM_001113549.1 NP_001107021.1 latent-transforming growth factor beta-binding protein 4 isoform b precursor
NM_001310678.1 NP_001297607.1 latent-transforming growth factor beta-binding protein 4 isoform 3 precursor
NM_175641.2 NP_783572.2 latent-transforming growth factor beta-binding protein 4 isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25713297 MGI
Biological Process GO Annotation Evidence References Source
involved in elastic fiber assembly IMP
IMP: Inferred from mutant phenotype
25713297 MGI
acts upstream of or within hormone secretion IMP
IMP: Inferred from mutant phenotype
12208849 MGI
acts upstream of or within transforming growth factor beta receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
12208849 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
12208849 MGI
located in microfibril IDA
IDA: Inferred from direct assay
19349279 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

latent-transforming growth factor beta-binding protein 4

  • LTBP-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07880 LTBP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ltbp4 NCBI NCBI:8425