2. Gene
  3. Ltbp4 - latent transforming growth factor beta binding protein 4 Gene

Ltbp4 - latent transforming growth factor beta binding protein 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2310046A13Rik

Gene ID: 108075 | Gene type: protein coding

About Ltbp4

Summary

Predicted to enable transforming growth factor beta binding activity. Involved in elastic fiber assembly. Acts upstream of or within hormone secretion and transforming growth factor beta receptor signaling pathway. Located in microfibril. Is expressed in aorta; blood vessel; ovary; and oviduct. Used to study cutis laxa. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IC. Orthologous to human LTBP4 (latent transforming growth factor beta binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Ltbp4 Products(3)

mRNA Protein Name
NM_001113549.1 NP_001107021.1 latent-transforming growth factor beta-binding protein 4 isoform b precursor
NM_001310678.1 NP_001297607.1 latent-transforming growth factor beta-binding protein 4 isoform 3 precursor
NM_175641.2 NP_783572.2 latent-transforming growth factor beta-binding protein 4 isoform a precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25713297 MGI
Biological Process GO Annotation Evidence Reference Source
involved in elastic fiber assembly IMP
IMP: Inferred from mutant phenotype
25713297 MGI
acts upstream of or within hormone secretion IMP
IMP: Inferred from mutant phenotype
12208849 MGI
acts upstream of or within transforming growth factor beta receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
12208849 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
12208849 MGI
located in microfibril IDA
IDA: Inferred from direct assay
19349279 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

latent-transforming growth factor beta-binding protein 4

LTBP-4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07880 LTBP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ltbp4 NCBI NCBI:8425