Med21 - mediator complex subunit 21 Gene

Mus musculus

Also known as Srb7; Surb7; D6Ertd782e; 0610007L03Rik

Gene ID: 108098 | Gene type: protein coding

About Med21

Summary

Predicted to enable transcription coactivator activity. Predicted to contribute to ubiquitin protein Ligase activity. Acts upstream of or within blastocyst development and stem cell population maintenance. Part of mediator complex. Orthologous to human MED21 (mediator complex subunit 21). [provided by Alliance of Genome Resources, Apr 2022]

Med21 Products(1)

mRNA	Protein	Name
NM_025315.3	NP_079591.1	mediator of RNA polymerase II transcription subunit 21

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11591653	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within blastocyst development	IMP IMP: Inferred from mutant phenotype	10500093	MGI
acts upstream of or within somatic stem cell population maintenance	IMP IMP: Inferred from mutant phenotype	20720539	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of mediator complex	IDA IDA: Inferred from direct assay	12093747	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mediator of RNA polymerase II transcription subunit 21

RNA polymerase II holoenzyme component SRB7	RNAPII complex component SRB7
SRB7 (supressor of RNA polymerase B) homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08292	MED21 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Med21	NCBI	NCBI:9412

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