B4gat1 - beta-1,4-glucuronyltransferase 1 Gene

Also Known as iGAT; iGNT; B3gnt1; B3gnt6; BETA3GNT1; 1500032M01Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 108902

Summary

Predicted to enable glucuronosyltransferase activity. Acts upstream of or within axon guidance and protein glycosylation. Predicted to be located in Golgi apparatus. Is expressed in several structures, including alimentary system; nervous system; reproductive system; respiratory system; and thymus. Used to study muscular dystrophy-dystroglycanopathy. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Orthologous to human B4GAT1 (beta-1,4-glucuronyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

B4gat1 Products (1)

mRNA	Protein	Name
NM_175383.2	NP_780592.1	beta-1,4-glucuronyltransferase 1

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within axon guidance	IMP IMP: Inferred from mutant phenotype	23217742	MGI
acts upstream of or within protein glycosylation	IMP IMP: Inferred from mutant phenotype	23217742	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
beta-1,4-glucuronyltransferase 1	I-beta-1,3-N-acetylglucosaminyltransferase N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 poly-N-acetyllactosam

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-E70179	β-1,4-Glucuronyltransferase 1		/	Unkown
HY-RS01326	B4GAT1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	B4gat1	NCBI	NCBI:11041