2. Gene
  3. LOC109648312 - Runx1 +23 hematopoietic stem cell enhancer Gene

LOC109648312 - Runx1 +23 hematopoietic stem cell enhancer Gene

  • Gene
Mus musculus
Gene ID: 109648312 | Gene type: biological region

About LOC109648312

Summary

This region represents a conserved enhancer element located in the first intron of the runt related transcription factor 1 (Runx1) gene. This element regulates stage-specific expression of the P1 and P2 promoters of Runx1 in cells of the hemetopoietic lineage. Histone cell cycle regulator (Hira) incorporates histone H3.3 in this region, which promotes enhancer activity. This sequence may also be negatively regulated by cytosine methylation. [provided by RefSeq, Feb 2017]