DDX52 - DExD-box helicase 52 Gene
Also Known as ROK1; HUSSY19
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 11056
About DDX52
Cytogenetic location: 17q12
Genomic coordinates (GRCh38): 17:37,609,739-37,643,446 (from NCBI)
This gene has 8 transcripts (splice variants), 1 gene allele, 200 orthologues and 38 paralogues. Ubiquitous expression in testis (RPKM 4.2), endometrium (RPKM 4.1) and 25 other tissues.
Summary
Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
DDX52 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001291476.2 | NP_001278405.1 | probable ATP-dependent RNA helicase DDX52 isoform 2 |
| NM_007010.5 | NP_008941.3 | probable ATP-dependent RNA helicase DDX52 isoform 1 |
DDX52 Protein Structure
DEAD
DEAD: DEAD/DEAH box helicase (189 - 362)
Helicase_C
Helicase_C: Helicase conserved C-terminal domain (432 - 507)
- 0
- 100
- 200
- 300
- 400
- 500
- 599 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
probable ATP-dependent RNA helicase DDX52 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Chromosome 17q12 Deletion Syndrome |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS03657 | DDX52 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | DDX52 | VGNC | VGNC:27975 |
| Mus musculus | DDX52 | MGD | MGI:1925644 |
| Macaca mulatta | DDX52 | VGNC | VGNC:71679 |
| Felis catus | DDX52 | VGNC | VGNC:61414 |
| Rattus norvegicus | DDX52 | RGD | RGD:621743 |
| Others | DDX52 | NCBI |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service