ADAM30 - ADAM metallopeptidase domain 30 Gene
Also Known as svph4
Species: Homo sapiens
About ADAM30
This gene has 1 transcript (splice variant), 353 orthologues and 20 paralogues.
Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is testis-specific and contains a polymorphic region, resulting in isoforms with varying numbers of C-terminal repeats. [provided by RefSeq, Jul 2008]
ADAM30 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_021794.4 | NP_068566.2 | disintegrin and metalloproteinase domain-containing protein 30 preproprotein |
ADAM30 Protein Structure
Pep_M12B_propep: Reprolysin family propeptide (41 - 160)
Reprolysin: Reprolysin (M12B) family zinc metalloprotease (203 - 393)
Disintegrin: Disintegrin (408 - 483)
ADAM_CR: ADAM cysteine-rich (485 - 596)
- 0
- 200
- 400
- 600
- 790 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
disintegrin and metalloproteinase domain-containing protein 30 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Inflammatory Bowel Disease 13 |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | ADAM30 | MGD | MGI:1918328 |
| Rattus norvegicus | ADAM30 | RGD | RGD:1594713 |
| Macaca mulatta | ADAM30 | VGNC | VGNC:99836 |
| Others | ADAM30 | NCBI |