2. Gene
  3. SOX21 - SRY-box transcription factor 21 Gene

SOX21 - SRY-box transcription factor 21 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SOX25

Gene ID: 11166 | Gene type: protein coding

About SOX21

Cytogenetic location: 13q32.1 Genomic coordinates (GRCh38): 13:94,709,622-94,712,545 (from NCBI)

This gene has 1 transcript (splice variant), 164 orthologues, 20 paralogues and is associated with 37 phenotypes.

Summary

SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]

SOX21 Products(1)

mRNA Protein Name
NM_007084.4 NP_009015.1 transcription factor SOX-21

SOX21 Protein Structure

HMG_box

HMG_box: HMG (high mobility group) box (8 - 76)

SOXp

SOXp: SOX transcription factor (77 - 95)

  • 0
  • 100
  • 200
  • 276 a.a.
Protein Preferred Names Protein Names

transcription factor SOX-21

SOX-A

Related Diseases

Diseases Alias
Lambert-Eaton Myasthenic Syndrome

Lambert-Eaton Syndrome

Eaton-Lambert Syndrome

Lems

Lambert Eaton Myasthenic Syndrome

Eaton Lambert Syndrome

Lambert Eaton Syndrome

Myasthenic Syndrome Of Lambert-Eaton

Myasthenic-Myopathic Syndrome Of Lambert-Eaton

Lems - [Lambert-Eaton Myasthenic Syndrome]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13592 SOX21 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SOX21 VGNC VGNC:102327
Mus musculus SOX21 MGD MGI:2654070
Bos taurus SOX21 VGNC VGNC:35147
Macaca mulatta SOX21 VGNC VGNC:106298
Rattus norvegicus SOX21 RGD RGD:1304724